Description

2-Brom-6-Fluoro-3-Formylphenylboronic Acid is a high-value, multi-functional boronic acid derivative used as a critical building block in advanced organic synthesis. Its unique structure, featuring bromo, fluoro, and formyl substituents on a phenylboronic acid core, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling and further functional group transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted therapies and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: The boronic acid functional group enables efficient palladium-catalyzed carbon-carbon bond formation with aryl/vinyl halides.
• Ligand and Catalyst Development: Used to synthesize novel bidentate or tridentate ligands for asymmetric catalysis.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and protein interactions.

Basic Information

Item	Details
Product Name	2-Brom-6-Fluoro-3-Formylphenylboronic Acid
CAS No.	1451392-81-6
Molecular Formula	C7H5BBrFO3
Molecular Weight	245.83 g/mol
Synonyms	(2-Bromo-6-fluoro-3-formylphenyl)boronic acid; 2-Bromo-6-fluorobenzaldehyde-3-boronic acid; 3-Borono-2-bromo-6-fluorobenzaldehyde; 2-Bromo-6-fluoro-3-carboxaldehydebenzeneboronic acid; Boronic acid, B-(2-bromo-6-fluoro-3-formylphenyl)-; 1451392-81-6
EINECS	Contact for details

Quality Control

Every batch of 2-Brom-6-Fluoro-3-Formylphenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.