Description

3-Aminocarbonyl-2-Fluorophenylboronic Acid is a high-value organoboron building block featuring both a boronic acid and a carboxamide functional group. This bifunctional nature makes it a critical intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the life sciences sector for constructing novel drug candidates, especially those targeting protease enzymes or requiring Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Suzuki-Miyaura Cross-Coupling: The boronic acid moiety enables efficient palladium-catalyzed carbon-carbon bond formation to create biaryl structures common in modern therapeutics.
• Protease Inhibitor Development: The fluorophenyl carboxamide scaffold is valuable for designing inhibitors for various protease targets.
• Chemical Biology & Proteomics: Used in the development of activity-based probes and molecular tools for studying enzyme function.
• Agrochemical Research: Intermediate in the discovery and synthesis of new crop protection agents with enhanced properties.
• Material Science: Potential monomer or linker for creating advanced polymeric materials and sensors.

Basic Information

Product Name	3-Aminocarbonyl-2-Fluorophenylboronic Acid
CAS No.	1451392-76-9
Molecular Formula	C7H7BFNO3
Molecular Weight	182.95 g/mol
Synonyms	2-Fluoro-3-carbamoylphenylboronic Acid; (3-Carbamoyl-2-fluorophenyl)boronic Acid; 2-Fluoro-3-aminocarbonylbenzeneboronic Acid; 3-Aminooxalyl-2-fluorophenylboronic Acid; B-(3-Carbamoyl-2-fluorophenyl)boronic Acid; 2-Fluorobenzamide-3-boronic Acid; 3-Borono-2-fluorobenzamide
EINECS	Contact for details

Quality Control

Every batch of 3-Aminocarbonyl-2-Fluorophenylboronic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications developed for research and pharmaceutical-grade intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.