Description

2,6-Difluoro-4-(Methylthio)Phenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a pivotal method for constructing complex biaryl and heterobiaryl structures. This compound is critically needed by pharmaceutical, agrochemical, and advanced materials researchers for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the difluoro and methylthio motifs enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as semiconductors for OLEDs and OFETs, where precise molecular architecture is required.
• Chemical Biology Probes: Utilized to create fluorinated molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs serving the global life sciences industry.

Basic Information

Product Name	2,6-Difluoro-4-(Methylthio)Phenylboronic Acid
CAS No.	1451392-53-2
Molecular Formula	C7H7BF2O2S
Molecular Weight	203.99 g/mol
Synonyms	2,6-Difluoro-4-(methylsulfanyl)benzeneboronic acid; 4-(Methylthio)-2,6-difluorophenylboronic acid; (2,6-Difluoro-4-(methylthio)phenyl)boronic acid; 2,6-Difluoro-4-methylsulfanylbenzeneboronic acid; B-[2,6-Difluoro-4-(methylthio)phenyl]boronic acid; 1451392-53-2; 2,6-Difluoro-4-methylmercaptophenylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-4-(Methylthio)Phenylboronic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity requirements for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and other relevant analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.