Description

2-Fluoro-3-(N,N-Dimethylaminocarbonyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group for Suzuki-Miyaura cross-coupling reactions with a dimethylamide moiety that can influence solubility and downstream reactivity. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who are developing novel active ingredients, particularly for creating complex biaryl structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used to construct novel herbicide and pesticide candidates containing fluorinated biaryl scaffolds.
• Material Science: Employed in the development of organic electronic materials, such as ligands for OLEDs or OFETs.
• Chemical Biology: Serves as a building block for creating molecular probes and enzyme inhibitors.
• Catalyst Ligand Synthesis: Utilized to prepare novel bidentate or monodentate ligands for transition metal catalysis.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	2-Fluoro-3-(N,N-Dimethylaminocarbonyl)Phenylboronic Acid
CAS No.	1451391-88-0
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	(2-Fluoro-3-(dimethylcarbamoyl)phenyl)boronic acid; 3-Borono-2-fluoro-N,N-dimethylbenzamide; 2-Fluoro-3-(dimethylcarbamoyl)benzeneboronic acid; B-[2-Fluoro-3-[(dimethylamino)carbonyl]phenyl]boronic acid; 1451391-88-0; 2-Fluoro-N,N-dimethyl-3-boronobenzamide
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-(N,N-Dimethylaminocarbonyl)Phenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.