Description

2-Ethoxy-4-Methylphenylboronic Acid is a versatile organoboron compound widely used as a key synthetic intermediate in cross-coupling reactions. Its primary value lies in enabling the efficient construction of complex biaryl and heterobiaryl structures, which are crucial scaffolds in advanced material and pharmaceutical chemistry. This high-purity boronic acid is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific biaryl motifs for efficacy.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and organic photovoltaics, where precise molecular architecture is key.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Product Name	2-Ethoxy-4-Methylphenylboronic Acid
CAS No.	1451391-71-1
Molecular Formula	C9H13BO3
Molecular Weight	180.01 g/mol
Synonyms	(2-Ethoxy-4-methylphenyl)boronic acid; 4-Methyl-2-ethoxyphenylboronic acid; 2-Ethoxy-p-tolylboronic acid; Boronic acid, B-(2-ethoxy-4-methylphenyl)-; 1451391-71-1; 2-Ethoxy-4-methylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-4-Methylphenylboronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.