Description

3,4-Difluoro-2-Ethoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing difluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic motifs.
• Material Science: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as a boronic acid reagent in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in lead optimization and route scouting for new compounds.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3,4-Difluoro-2-Ethoxyphenylboronic Acid
CAS No.	1451391-69-7
Molecular Formula	C8H9BF2O3
Molecular Weight	201.97 g/mol
Synonyms	(3,4-Difluoro-2-ethoxyphenyl)boronic acid; 2-Ethoxy-3,4-difluorophenylboronic acid; B-(3,4-Difluoro-2-ethoxyphenyl)boronic acid; 3,4-Difluoro-2-ethoxybenzeneboronic acid; 1451391-69-7; AKOS025311315; FT-0776939
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-Ethoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request, providing full traceability and quality assurance for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.