Description

6-Ethoxy-2-Fluoro-3-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic structures.
• Material Science: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new catalytic processes and constructing molecular libraries.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as a boronic acid coupling partner with aryl halides or triflates to form carbon-carbon bonds under palladium catalysis.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Ethoxy-2-Fluoro-3-Methylphenylboronic Acid
CAS No.	1451391-66-4
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	(6-Ethoxy-2-fluoro-3-methylphenyl)boronic acid; 2-Fluoro-6-ethoxy-3-methylbenzeneboronic acid; 3-Methyl-2-fluoro-6-ethoxybenzeneboronic acid; Boronic acid, B-(6-ethoxy-2-fluoro-3-methylphenyl)-; 1451391-66-4; 6-Ethoxy-2-fluoro-3-methylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 6-Ethoxy-2-Fluoro-3-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.