Description

2-Chloro-3,5-Dimethylphenylboronic acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for constructing complex aromatic and heteroaromatic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific chlorinated dimethylphenyl motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is crucial.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Chloro-3,5-Dimethylphenylboronic acid
CAS No.	1451391-50-6
Molecular Formula	C8H10BClO2
Molecular Weight	184.43 g/mol
Synonyms	(2-Chloro-3,5-dimethylphenyl)boronic acid; 2-Chloro-3,5-dimethylbenzeneboronic acid; B-(2-Chloro-3,5-dimethylphenyl)boronic acid; 2-Chloro-3,5-dimethylphenylboronic acid; Boronic acid, B-(2-chloro-3,5-dimethylphenyl)-; 1451391-50-6; 2-Chloro-3,5-xylylboronic acid
EINECS	Contact for details

Quality Control

Every batch of our 2-Chloro-3,5-Dimethylphenylboronic acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high purity suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) providing results for identity, purity (typically by HPLC/NMR), and impurity profile is provided with each shipment to ensure traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.