Description

3-(4-Bromo-2,6-Dimethylphenylcarbamoyl)-4-Fluorophenylboronic Acid is a sophisticated boronic acid derivative designed for advanced synthetic chemistry applications. This compound serves as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is essential for chemists and researchers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, structurally precise intermediates for cross-coupling reactions and other pivotal transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting specific receptors or enzymes.
• Suzuki-Miyaura Cross-Coupling Reactions: Functions as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific halogenated and fluorinated aromatic motifs.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and organic photovoltaics, where its molecular structure can influence charge transport properties.
• Chemical Biology & Probe Development: Utilized for creating molecular probes and labeled compounds for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic projects requiring high-fidelity intermediates.

Basic Information

Item	Details
Product Name	3-(4-Bromo-2,6-Dimethylphenylcarbamoyl)-4-Fluorophenylboronic Acid
CAS No.	1451391-49-3
Molecular Formula	C15H14BBrFNO3
Molecular Weight	378.00 g/mol
Synonyms	[4-Fluoro-3-[[(4-bromo-2,6-dimethylphenyl)amino]carbonyl]phenyl]boronic acid; 3-[(4-Bromo-2,6-dimethylphenyl)carbamoyl]-4-fluorobenzeneboronic acid; 4-Fluoro-3-((4-bromo-2,6-dimethylphenyl)carbamoyl)phenylboronic acid; Boronic acid, B-[4-fluoro-3-[[(4-bromo-2,6-dimethylphenyl)amino]carbonyl]phenyl]-; 1451391-49-3
EINECS	Contact for details

Quality Control

Our 3-(4-Bromo-2,6-Dimethylphenylcarbamoyl)-4-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and other high-precision industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.