Description

2-Bromo-6-Fluoro-4-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing complex, multi-substituted biphenyl or heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific halogenated and fluorinated aromatic systems.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a core structure in metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and inhibitors for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs (Contract Research Organizations) serving the global life sciences industry.

Basic Information

Item	Details
Product Name	2-Bromo-6-Fluoro-4-Methylphenylboronic Acid
CAS No.	1451391-47-1
Molecular Formula	C7H7BBrFO2
Molecular Weight	232.85 g/mol
Synonyms	(2-Bromo-6-fluoro-4-methylphenyl)boronic acid; 2-Bromo-6-fluoro-p-tolylboronic acid; B-(2-Bromo-6-fluoro-4-methylphenyl)boronic acid; 2-Bromo-6-fluoro-4-methylbenzeneboronic acid; 1451391-47-1; Boronic acid, B-(2-bromo-6-fluoro-4-methylphenyl)-; 4-Methyl-2-bromo-6-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-Fluoro-4-Methylphenylboronic Acid is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and consistent performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be stored away from direct light exposure. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.