Description

6-Benzyloxy-2-Fluoro-3-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who are developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic systems.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and inhibitors for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical suppliers and CROs/CMOs offering bespoke synthesis services for client projects.
• Academic & Industrial R&D: Fundamental research tool in university and corporate laboratories for methodology development and exploring new chemical spaces.

Basic Information

Product Name	6-Benzyloxy-2-Fluoro-3-Methylphenylboronic Acid
CAS No.	1451391-39-1
Molecular Formula	C14H14BFO3
Molecular Weight	260.07 g/mol
Synonyms	(6-(Benzyloxy)-2-fluoro-3-methylphenyl)boronic acid; 2-Fluoro-3-methyl-6-(phenylmethoxy)benzeneboronic acid; 6-Benzyloxy-2-fluoro-3-methylbenzeneboronic acid; B-(6-Benzyloxy-2-fluoro-3-methylphenyl)boronic acid; 1451391-39-1; AKOS026710693
EINECS	Contact for details

Quality Control

Every batch of 6-Benzyloxy-2-Fluoro-3-Methylphenylboronic Acid is produced and tested under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemicals and advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via techniques such as HPLC, NMR, and MS is provided with each shipment to guarantee reproducible performance in your critical coupling reactions.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.