Description

4-Bromo-2,5-Bifluorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is specifically designed for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for constructing complex fluorinated and brominated aromatic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing difluorophenyl and bromophenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that benefit from the unique properties of fluorinated compounds.
• Material Science: Serves as a precursor in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Diagnostics: Utilized in the preparation of molecular probes and diagnostic agents where specific fluorinated aromatic structures are required.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Bromo-2,5-Bifluorophenylboronic Acid Pinacol Ester
CAS No.	1451391-15-3
Molecular Formula	C₁₂H₁₄BBrF₂O₂
Molecular Weight	319.0 g/mol
Synonyms	4-Bromo-2,5-difluorophenylboronic Acid Pinacol Ester; 2-(4-Bromo-2,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-Bromo-2,5-difluorophenyl)boronic Acid Pinacol Ester; 4-Bromo-2,5-Bifluorophenyl BPin; 4-Bromo-2,5-Bifluorophenyl-Bpin; 4-Bromo-2,5-difluorophenyl-Bpin; 4-Bromo-2,5-difluorophenylboronic Acid, Pinacol Ester; 4-Bromo-2,5-difluorophenylboronic Acid Pinacolate
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,5-Bifluorophenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.