Description

2-Fluoro-3-Isopropoxyphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound is critical for modern cross-coupling reactions, enabling the efficient construction of complex molecules for advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials scientists for the synthesis of novel active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, including herbicides and fungicides with novel modes of action.
• Liquid Crystal & OLED Material Development: Serves as a precursor in the synthesis of fluorinated aromatic compounds for electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Material Science: Enables the incorporation of functionalized aryl groups into polymer backbones to modify thermal stability, solubility, and electronic properties.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugates for studying biological processes and diagnostic applications.
• Catalyst & Ligand Design: Acts as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2-Fluoro-3-Isopropoxyphenylboronic Acid Pinacol Ester
CAS No.	1451391-00-6
Molecular Formula	C15H22BFO3
Molecular Weight	280.14 g/mol
Synonyms	2-Fluoro-3-isopropoxybenzeneboronic acid pinacol ester; (2-Fluoro-3-isopropoxyphenyl)boronic acid pinacol ester; 2-Fluoro-3-(propan-2-yloxy)phenylboronic acid pinacol ester; Pinacol (2-fluoro-3-isopropoxyphenyl)boronate; B-[2-Fluoro-3-(1-methylethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-[2-fluoro-3-(1-methylethoxy)phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; 1451391-00-6
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Isopropoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee reproducible performance in sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.