Description

3,4-Difluoro-2-isopropoxyphenylboronic acid is a high-purity organoboron compound serving as a versatile building block in modern synthetic chemistry. Its value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the difluoro and isopropoxy substituents confer specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and semiconductors, where precise fluorination patterns are crucial.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	3,4-Difluoro-2-isopropoxyphenylboronic Acid
CAS No.	1451390-92-3
Molecular Formula	C9H11BF2O3
Molecular Weight	216.00 g/mol
Synonyms	(3,4-Difluoro-2-isopropoxyphenyl)boronic acid; 2-Isopropoxy-3,4-difluorophenylboronic acid; Boronic acid, B-(3,4-difluoro-2-isopropoxyphenyl)-; 1451390-92-3; 3,4-Difluoro-2-(1-methylethoxy)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-isopropoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all specifications are provided to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to minimize exposure to moisture and oxygen, which can affect stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.