Description

4-Acetyl-2,3-Difluorophenylboronic Acid is a specialized organoboron compound featuring both an acetyl and a boronic acid functional group on a difluorinated aromatic ring. This unique structure makes it a highly valuable building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a monomer or linker for creating advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the development of molecular probes and sensors for diagnostic applications.
• Catalyst Ligand Development: The boronic acid group can be utilized to create novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: An essential reagent for fine chemical suppliers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	4-Acetyl-2,3-Difluorophenylboronic Acid
CAS No.	1451390-78-5
Molecular Formula	C8H7BF2O3
Molecular Weight	199.95 g/mol
Synonyms	(4-Acetyl-2,3-difluorophenyl)boronic Acid; 2,3-Difluoro-4-acetylbenzeneboronic Acid; 4-Acetyl-2,3-difluorobenzeneboronic Acid; Boronic acid, B-(4-acetyl-2,3-difluorophenyl)-; 1451390-78-5; 4-Acetyl-2,3-difluorophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 4-Acetyl-2,3-Difluorophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.