Description

4-(Methoxycarbonyl)-3-(Trifluoromethyl)Phenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling precise cross-coupling reactions to construct complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing drug candidates, particularly those containing trifluoromethyl and ester groups.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the creation of novel boron-containing ligands for catalytic systems and chemical sensors.
• Chemical Library Construction: A valuable building block for combinatorial chemistry and high-throughput screening in drug discovery programs.
• Academic & R&D: Used in university and corporate research laboratories for methodological studies in organoboron chemistry and synthetic route development.

Basic Information

Product Name	4-(Methoxycarbonyl)-3-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1451375-04-4
Molecular Formula	C9H8BF3O4
Molecular Weight	247.97 g/mol
Synonyms	Methyl 4-Borono-2-(trifluoromethyl)benzoate; 2-(Trifluoromethyl)-4-(methoxycarbonyl)benzeneboronic Acid; (4-(Methoxycarbonyl)-3-(trifluoromethyl)phenyl)boronic Acid; 4-Carbomethoxy-3-trifluoromethylphenylboronic Acid; Methyl 2-(trifluoromethyl)-4-boronobenzoate; B-[4-(Methoxycarbonyl)-3-(trifluoromethyl)phenyl]boronic Acid
EINECS	Contact for details

Quality Control

Our 4-(Methoxycarbonyl)-3-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect purity and reactivity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.