Description

(3-(Trifluoromethyl)-1H-Indazol-5-Yl)Boronic Acid is a high-purity boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its value lies in its role as a versatile building block for the Suzuki-Miyaura cross-coupling reaction, a cornerstone method for forming carbon-carbon bonds. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly those containing the indazole and trifluoromethyl pharmacophores.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the metabolic stability imparted by the trifluoromethyl group.
• Material Science Research: Serves as a precursor for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, through cross-coupling polymerization.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development in cross-coupling catalysis and heterocyclic chemistry.

Basic Information

Product Name	(3-(Trifluoromethyl)-1H-Indazol-5-Yl)Boronic Acid
CAS No.	1451154-24-7
Molecular Formula	C8H6BF3N2O2
Molecular Weight	229.96 g/mol
Synonyms	5-Borono-3-(trifluoromethyl)-1H-indazole; [5-(Trifluoromethyl)-1H-indazol-3-yl]boronic acid; 3-Trifluoromethyl-1H-indazole-5-boronic acid; (3-Trifluoromethyl-1H-indazol-5-yl)boronic acid; B-[3-(Trifluoromethyl)-1H-indazol-5-yl]boronic acid; 5-Boron-3-(trifluoromethyl)-1H-indazole; 1H-Indazole-5-boronic acid, 3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our (3-(Trifluoromethyl)-1H-Indazol-5-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.