Description

(2S)-6-[[(E)-But-2-Enoyl]Amino]-2-(9H-Fluoren-9-Ylmethoxycarbonylamino)Hexanoic Acid is a specialized, high-purity Fmoc-protected amino acid derivative designed for advanced peptide synthesis and pharmaceutical research. This compound is critical for constructing complex peptide sequences with specific stereochemistry and functional groups, ensuring high coupling efficiency and minimal racemization. It is an essential building block for researchers and manufacturers in pharmaceutical development, proteomics, and the production of therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated synthesis of complex peptides.
• Pharmaceutical Intermediate: Used in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptidomimetic Design: Serves as a crucial component for creating modified peptide analogs with enhanced stability or biological activity.
• Bioconjugation: Facilitates the site-specific labeling or functionalization of peptides and proteins for diagnostic and research applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Industrial Research: A fundamental reagent for studies in biochemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	(2S)-6-[[(E)-But-2-Enoyl]Amino]-2-(9H-Fluoren-9-Ylmethoxycarbonylamino)Hexanoic Acid
CAS No.	1451046-72-2
Molecular Formula	C29H30N2O5
Molecular Weight	486.56 g/mol
Synonyms	Fmoc-L-Lys(Crotonyl)-OH; Nε-Crotonyl-Nα-Fmoc-L-lysine; Fmoc-Lys(Crotonyl)-OH; (2S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-6-((E)-but-2-enamido)hexanoic acid; N-α-Fmoc-N-ε-crotonyl-L-lysine; Fmoc-Lys(Crotonoyl)-OH; Fmoc-L-Lysine(Crotonic Acid) derivative; Nα-Fmoc-Nε-crotonyl-L-lysine
EINECS	Contact for details

Quality Control

Our (2S)-6-[[(E)-But-2-Enoyl]Amino]-2-(9H-Fluoren-9-Ylmethoxycarbonylamino)Hexanoic Acid is manufactured under strict quality management systems to ensure the high purity and consistency required for sensitive research and cGMP applications. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, chiral purity, and chemical composition. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.