Description

Hs-Peg5-Ch2Ch2N3 is a heterobifunctional polyethylene glycol (PEG) linker featuring a hydroxyl group and an azide moiety, designed for precise bioconjugation and click chemistry applications. This compound is essential for creating stable, well-defined conjugates in pharmaceutical development and advanced material science. It is primarily utilized by researchers and manufacturers in the fields of biopharmaceuticals, diagnostics, and polymer chemistry who require reliable, high-purity linkers for drug delivery systems, surface functionalization, and hydrogel fabrication.

Application

• Bioconjugation and ADC Development: Used as a spacer arm to link antibodies, proteins, or peptides with cytotoxic drugs, fluorophores, or other payloads for targeted therapies and diagnostics.
• Click Chemistry Reagent: The terminal azide group enables efficient, copper-catalyzed or strain-promoted cycloaddition with alkynes for labeling and cross-linking biomolecules.
• Polymer and Material Modification: Serves as a functional modifier to introduce hydrophilic PEG chains and reactive sites onto surfaces, nanoparticles, or polymer backbones.
• Hydrogel and Biomaterial Fabrication: Acts as a cross-linking agent or functional component in the synthesis of biocompatible hydrogels for tissue engineering and controlled release systems.
• Diagnostic Assay Development: Facilitates the stable immobilization of capture molecules (e.g., antibodies, oligonucleotides) onto solid supports for ELISA, biosensors, and microarray platforms.
• Prodrug Synthesis: Employed to create cleavable linkages between therapeutic agents and masking groups, enabling controlled drug activation.

Basic Information

Item	Detail
Product Name	Hs-Peg5-Ch2Ch2N3
CAS No.	1449390-11-7
Molecular Formula	C19H37N3O7
Molecular Weight	419.52 g/mol
Synonyms	5-Azido-3,6,9,12,15-pentaoxa-2-azaheptadecan-17-ol; Heterobifunctional PEG5 linker, hydroxyl-PEG5-azide; Azido-PEG5-alcohol; N3-PEG5-OH; 17-Hydroxy-3,6,9,12,15-pentaoxa-2-azaheptadecan-5-azide; HS-(CH2)2-(OCH2CH2)5-N3; PEG-based azide linker
EINECS	Contact for details

Quality Control

Our Hs-Peg5-Ch2Ch2N3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, cool environment. Due to its hygroscopic and oxidizable nature, allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.