Description

Benzene, 4-Bromo-1-Cyclohexyl-2-(Trifluoromethyl)- is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is engineered to serve as a critical intermediate in the development of complex molecules, offering unique reactivity from its bromo and trifluoromethyl substituents. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for introducing lipophilic and electron-withdrawing groups.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings.
• Fluorine Chemistry: An important reagent for studying structure-activity relationships (SAR) in medicinal chemistry due to the presence of the trifluoromethyl group.
• Chemical Library Development: Used in high-throughput screening and combinatorial chemistry to create diverse compound libraries for biological testing.

Basic Information

Product Name	Benzene, 4-Bromo-1-Cyclohexyl-2-(Trifluoromethyl)-
CAS No.	1449291-53-5
Molecular Formula	C13H14BrF3
Molecular Weight	307.15 g/mol
Synonyms	4-Bromo-1-cyclohexyl-2-(trifluoromethyl)benzene; 1-Bromo-4-cyclohexyl-3-(trifluoromethyl)benzene; 4-Bromo-α,α,α-trifluoro-1-cyclohexyl-o-xylene; [1,1'-Biphenyl]-4-carbonitrile, 3'-bromo-4'-(trifluoromethyl)-; 3'-Bromo-4'-(trifluoromethyl)[1,1'-biphenyl]-4-carbonitrile; 4-Bromo-1-cyclohexyl-2-trifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our Benzene, 4-Bromo-1-Cyclohexyl-2-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.