Description

4-Fluoro-3-(4-Methylpiperazine-1-Carbonyl)-Phenyl Boronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a fluorinated aromatic ring and a piperazine amide moiety, enabling precise molecular construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Employed in the creation of advanced organic electronic materials and functional polymers.
• Chemical Biology: Serves as a probe or linker in bioconjugation and the development of biochemical tools.
• Suzuki-Miyaura Cross-Coupling: The boronic acid group is pivotal for forming carbon-carbon bonds in complex molecule assembly.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	4-Fluoro-3-(4-Methylpiperazine-1-Carbonyl)-Phenyl Boronic Acid
CAS No.	1449135-54-9
Molecular Formula	C13H18BFN2O3
Molecular Weight	280.11 g/mol
Synonyms	[4-Fluoro-3-(4-methylpiperazine-1-carbonyl)phenyl]boronic acid; 3-Carboxy-4-fluorophenylboronic acid 4-methylpiperazide; 4-Fluoro-3-[(4-methyl-1-piperazinyl)carbonyl]benzeneboronic acid; 4-Fluoro-3-(4-methylpiperazine-1-carbonyl)benzeneboronic acid; 1449135-54-9; BCP31131; AKOS025147064; ZINC000257777777
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-3-(4-Methylpiperazine-1-Carbonyl)-Phenyl Boronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.