Description

n-[(2,5-Dimethylphenyl)Sulfonyl]Phenylalanine is a specialized sulfonamide derivative of the amino acid phenylalanine, designed for advanced research and development applications. This high-purity synthetic intermediate is critical for medicinal chemistry programs, particularly in the design and synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams, agrochemical researchers, and fine chemical manufacturers seeking to develop new enzyme inhibitors or receptor modulators.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially protease or kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities for therapeutic targets.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled compounds or affinity probes in biochemical assays.
• Agrochemical Synthesis: Intermediate in the development of new crop protection agents with specific mode-of-action.
• Peptidomimetic Design: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.
• Fine Chemical Production: Used in custom synthesis for high-value, low-volume specialty chemicals.

Basic Information

Product Name	n-[(2,5-Dimethylphenyl)Sulfonyl]Phenylalanine
CAS No.	1449133-74-7
Molecular Formula	C17H19NO4S
Molecular Weight	333.40 g/mol
Synonyms	N-(2,5-Dimethylphenylsulfonyl)phenylalanine; (2S)-2-Amino-3-[4-[(2,5-dimethylphenyl)sulfonyl]phenyl]propanoic acid; L-Phenylalanine, N-[(2,5-dimethylphenyl)sulfonyl]-; 1449133-74-7; (S)-2-((2,5-Dimethylphenyl)sulfonamido)-3-phenylpropanoic acid; N-(2,5-Xylylsulfonyl)-L-phenylalanine; Tosyl-phenylalanine analog
EINECS	Contact for details

Quality Control

Our n-[(2,5-Dimethylphenyl)Sulfonyl]Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.