Description

(3-(Cyclopentylcarbamoyl)-4-Fluorophenyl)Boronic Acid is a high-purity, advanced pharmaceutical intermediate and building block. This compound is critical for modern synthetic chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting specific enzyme inhibitors or receptor modulators.
• Suzuki-Miyaura Cross-Coupling: Essential boronic acid reagent for forming carbon-carbon bonds to create biaryl structures, a common motif in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Potential precursor for creating organic electronic materials or metal-organic frameworks (MOFs) with specific fluorinated properties.
• Chemical Biology Probes: Serves as a versatile handle for labeling or modifying biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized boronic acid derivatives.

Basic Information

Item	Details
Product Name	(3-(Cyclopentylcarbamoyl)-4-Fluorophenyl)Boronic Acid
CAS No.	1449132-66-4
Molecular Formula	C₁₂H₁₅BFNO₃
Molecular Weight	251.07 g/mol
Synonyms	4-Fluoro-3-[(cyclopentylamino)carbonyl]benzeneboronic Acid; (4-Fluoro-3-((cyclopentylcarbamoyl)phenyl)boronic Acid; 3-Carbamoyl-4-fluorobenzeneboronic Acid Cyclopentyl Amide; B-[3-[(Cyclopentylamino)carbonyl]-4-fluorophenyl]boronic Acid; 1449132-66-4; (3-(Cyclopentylcarbamoyl)-4-fluorophenyl)boronic acid; Cyclopentyl-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-fluorophenyl]carbamate (protected form)
EINECS	Contact for details

Quality Control

Our (3-(Cyclopentylcarbamoyl)-4-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.