Description

(2-Fluoro-4-(4-Methylpiperidine-1-Carbonyl)Phenyl)Boronic Acid is a high-value, synthetically versatile organoboronic acid derivative. This compound matters as a critical building block in modern pharmaceutical and agrochemical research, enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of complex bioactive molecules and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient and selective formation of biaryl and heterobiaryl structures, which are common motifs in medicinal chemistry.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its ability to introduce complex fluorinated aromatic systems.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced organic electronic materials and polymers.
• Chemical Biology Probe Development: Utilized for labeling and modifying biomolecules to study biological pathways and protein function.
• Process Chemistry & Scale-up: Employed in the optimization and commercial-scale production of target molecules requiring this specific boronic acid moiety.

Basic Information

Product Name	(2-Fluoro-4-(4-Methylpiperidine-1-Carbonyl)Phenyl)Boronic Acid
CAS No.	1449131-89-8
Molecular Formula	C13H17BFNO3
Molecular Weight	265.09 g/mol
Synonyms	[2-Fluoro-4-(4-methyl-1-piperidinyl)carbonyl]phenylboronic acid; 2-Fluoro-4-[(4-methylpiperidin-1-yl)carbonyl]benzeneboronic acid; 4-(4-Methylpiperidine-1-carbonyl)-2-fluorophenylboronic acid; B-[2-Fluoro-4-(4-methyl-1-piperidinyl)carbonyl]phenyl]boronic acid; (2-Fluoro-4-((4-methylpiperidin-1-yl)carbonyl)phenyl)boronic acid; 1449131-89-8; Boronic acid, B-[2-fluoro-4-[(4-methyl-1-piperidinyl)carbonyl]phenyl]-
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-(4-Methylpiperidine-1-Carbonyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.