Description

(3-Fluoro-4-(Morpholinosulfonyl)Phenyl)Boronic Acid is a sophisticated organoboron building block featuring a unique combination of a boronic acid group, a fluorine substituent, and a morpholinosulfonyl moiety. This compound is highly valued as a key intermediate in modern synthetic chemistry, particularly for cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily needed by pharmaceutical and agrochemical R&D teams, as well as advanced material scientists, for constructing complex molecular architectures. Its specific structure makes it essential for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting CNS disorders, oncology, and inflammation.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by introducing the fluorinated phenylboronic acid motif into lead structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for palladium-catalyzed coupling with aryl/heteroaryl halides to form biaryl linkages, a cornerstone of medicinal chemistry.
• Material Science: Potential monomer or precursor for synthesizing advanced polymers, liquid crystals, or organic electronic materials requiring specific electronic properties.
• Chemical Biology & Probe Development: Utilized in designing molecular probes and sensors that leverage the boronic acid group's affinity for diols or the fluorine atom as a spectroscopic label.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	(3-Fluoro-4-(Morpholinosulfonyl)Phenyl)Boronic Acid
CAS No.	1447713-89-4
Molecular Formula	C10H13BFNO4S
Molecular Weight	273.09 g/mol
Synonyms	[4-(Morpholine-4-sulfonyl)-3-fluorophenyl]boronic acid; 3-Fluoro-4-(morpholine-4-sulfonyl)benzeneboronic acid; (3-Fluoro-4-morpholinosulfonylphenyl)boronic acid; B-[3-Fluoro-4-(4-morpholinylsulfonyl)phenyl]boronic acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluorophenyl morpholinosulfonate (protected form); 1447713-89-4; Boronic acid, B-[3-fluoro-4-(4-morpholinylsulfonyl)phenyl]-
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-(Morpholinosulfonyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (argon/nitrogen) when opening to prevent degradation. For long-term storage, consider desiccated conditions at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.