Description

(3-Fluoro-4-((4-Methylpiperazin-1-yl)sulfonyl)phenyl)boronic acid is a high-value, multi-functional boronic acid derivative designed for advanced synthetic chemistry. Its core value lies in its dual functionality, combining a reactive boronic acid group for Suzuki-Miyaura cross-coupling with a sulfonamide-linked methylpiperazine moiety that offers excellent solubility and potential for further derivatization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a critical building block for creating novel, complex molecules targeting a range of therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Suzuki-Miyaura Cross-Coupling: The boronic acid functional group enables efficient palladium-catalyzed cross-coupling with aryl/heteroaryl halides, facilitating the construction of complex biaryl and heterobiaryl scaffolds.
• Protease Inhibitor Development: The sulfonamide and methylpiperazine structure is commonly found in inhibitors for various enzymes, making this compound valuable for medicinal chemistry programs focused on protease targets.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides that require sophisticated aromatic and heterocyclic structures.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers, metal-organic frameworks (MOFs), or organic electronic materials.
• Chemical Biology & Probe Design: Utilized for synthesizing molecular probes and bioconjugates to study biological pathways and protein-ligand interactions.

Basic Information

Product Name	(3-Fluoro-4-((4-Methylpiperazin-1-yl)sulfonyl)phenyl)boronic Acid
CAS No.	1447713-71-4
Molecular Formula	C11H16BFN2O4S
Molecular Weight	302.13 g/mol
Synonyms	[3-Fluoro-4-(4-methylpiperazine-1-sulfonyl)phenyl]boronic acid; (3-Fluoro-4-((4-methyl-1-piperazinyl)sulfonyl)phenyl)boronic acid; B-[3-Fluoro-4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]boronic acid; 4-Borono-2-fluoro-N-(4-methylpiperazin-1-yl)benzenesulfonamide; 3-Fluoro-4-(4-methylpiperazine-1-sulfonyl)benzeneboronic acid; Boronic acid, B-[3-fluoro-4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-; 1447713-71-4
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-((4-Methylpiperazin-1-yl)sulfonyl)phenyl)boronic acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements of research and development. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and reactivity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.