Description

1,3-Dibromo-2-Ethoxy-5-Fluorobenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its precise substitution pattern, which makes it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for bioactivity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms can enhance metabolic stability and binding affinity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated structure.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling the introduction of complex aryl groups.
• Chemical Library Development: Employed in medicinal chemistry for the parallel synthesis and creation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	1,3-Dibromo-2-Ethoxy-5-Fluorobenzene
CAS No.	1447671-86-4
Molecular Formula	C8H7Br2FO
Molecular Weight	305.95 g/mol
Synonyms	2-Ethoxy-1,3-dibromo-5-fluorobenzene; 5-Fluoro-1,3-dibromo-2-ethoxybenzene; 1,3-Dibromo-5-fluoro-2-ethoxybenzene; Benzene, 1,3-dibromo-2-ethoxy-5-fluoro-; 1447671-86-4; 2-Ethoxy-5-fluoro-1,3-dibromobenzene
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-2-Ethoxy-5-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.