Description

1-Bromo-2-Fluoro-4-Iodo-5-Methoxy-Benzene is a highly functionalized halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and process chemists developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty ligands for catalysis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides, herbicides, and fungicides with specific activity profiles.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A versatile reagent in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution for introducing complex aromatic systems.
• Ligand Synthesis: Useful for preparing sophisticated ligands used in homogeneous catalysis and coordination chemistry.
• Dye & Pigment Industry: Intermediate for synthesizing complex halogenated dyes and functional pigments.

Basic Information

Product Name	1-Bromo-2-Fluoro-4-Iodo-5-Methoxy-Benzene
CAS No.	1447671-70-6
Molecular Formula	C7H5BrFIO
Molecular Weight	330.92 g/mol
Synonyms	2-Bromo-1-Fluoro-4-Iodo-5-Methoxybenzene; 5-Methoxy-2-bromo-1-fluoro-4-iodobenzene; Benzene, 1-bromo-2-fluoro-4-iodo-5-methoxy-; 1-Bromo-2-fluoro-4-iodo-5-methoxybenzene; 4-Bromo-3-fluoro-6-iodoanisole
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoro-4-Iodo-5-Methoxy-Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity and impurity profiles. Our quality management system adheres to cGMP principles where applicable, ensuring reliable supply for critical development and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.