Description

5-Ethoxy-2-Fluorophenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and ethoxy-substituted aromatic systems.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides where the specific substitution pattern can influence bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Utilized in the development of organic semiconductors, liquid crystals, and polymers with tailored electronic properties.
• Chemical Biology Probes: Serves as a building block for creating molecular probes and tags used in biochemical research and diagnostics.

Basic Information

Item	Detail
Product Name	5-Ethoxy-2-Fluorophenylboronic Acid Pinacol Ester
CAS No.	1445601-63-7
Molecular Formula	C14H20BFO3
Molecular Weight	266.12 g/mol
Synonyms	2-Fluoro-5-ethoxyphenylboronic acid pinacol ester; (5-Ethoxy-2-fluorophenyl)boronic acid pinacol ester; 5-Ethoxy-2-fluorobenzeneboronic acid pinacol ester; 2-Fluoro-5-ethoxybenzeneboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(5-ethoxy-2-fluorophenyl)-1,3,2-dioxaborolane; Pinacol (5-Ethoxy-2-fluorophenyl)boronate
EINECS	Contact for details

Quality Control

Every batch of 5-Ethoxy-2-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard quality protocol includes comprehensive analysis by NMR, HPLC, and GC to verify identity, assay, and impurity profiles. Certificates of Analysis (COA) detailing all test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.