Description

4-Isopropoxy-3-(Trifluoromethyl)Phenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing trifluoromethyl and aryl ether motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Building block for creating advanced organic electronic materials, liquid crystals, and polymers via palladium-catalyzed coupling.
• Chemical Research & Development: Essential reagent in medicinal chemistry and process chemistry for constructing biaryl and heterobiaryl structures.
• Custom Synthesis: Serves as a specialized starting material for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Product Name	4-Isopropoxy-3-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1444260-43-8
Molecular Formula	C10H12BF3O3
Molecular Weight	248.01 g/mol
Synonyms	[4-(Isopropoxy)-3-(trifluoromethyl)phenyl]boronic acid; 3-Trifluoromethyl-4-isopropoxyphenylboronic acid; 4-Isopropoxy-3-trifluoromethylbenzeneboronic acid; 4-(1-Methylethoxy)-3-(trifluoromethyl)benzeneboronic acid; Boronic acid, B-[4-(1-methylethoxy)-3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 4-Isopropoxy-3-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.