Description

(S)-3,3'-Bis(3,5-Di-tert-Butylphenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is a high-value, chiral organophosphorus compound that serves as a sophisticated ligand and catalyst precursor in advanced chemical synthesis. Its primary commercial value lies in enabling highly enantioselective transformations, which are critical for producing single-isomer pharmaceuticals and fine chemicals. This product is essential for R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop and manufacture optically pure active ingredients.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal catalysts (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, C-C bond formation, and other key synthetic steps.
• Pharmaceutical Intermediate Synthesis: Critical for the production of chiral active pharmaceutical ingredients (APIs) where high enantiomeric excess (ee) is required for efficacy and safety.
• Agrochemical Development: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the development of chiral polymers, liquid crystals, and advanced functional materials.
• Academic & Industrial R&D: A valuable tool for method development and discovery chemistry in asymmetric synthesis.

Basic Information

Product Name	(S)-3,3'-Bis(3,5-Di-tert-Butylphenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	1442645-05-7
Molecular Formula	C54H61O4P
Molecular Weight	829.03 g/mol
Synonyms	(S)-3,3'-Bis(3,5-di-tert-butylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (S)-3,3'-Bis(3,5-di-tert-butylphenyl)-BINOL phosphate; (S)-DTB-BINOL phosphate; (S)-BINOL derivative phosphate ligand; Chiral binaphthyl phosphate; (S)-H8-BINOL-based phosphate (analogous class); Asymmetric organocatalyst precursor; Chiral phosphoric acid derivative
EINECS	Contact for details

Quality Control

Every batch of (S)-3,3'-Bis(3,5-Di-tert-Butylphenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is produced and analyzed under strict quality management protocols to ensure consistency and high performance in sensitive asymmetric applications. Our standard quality commitment includes comprehensive analysis for chiral purity (enantiomeric excess), chemical purity, and identity verification. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and chiral integrity. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.