Description

n-[(9S)-8Alpha-Cinchonan-9-Yl]Quinoline-8-Sulfonamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex chiral structure. This compound matters for its critical role in the synthesis of specialized active pharmaceutical ingredients (APIs), particularly those targeting neurological and anti-malarial pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing and scaling up next-generation therapeutic agents. Its precise stereochemistry is essential for ensuring the efficacy and safety of the final drug product.

Application

• Key chiral intermediate in the research and development of novel pharmaceutical compounds.
• Building block for the synthesis of complex alkaloid-derived active pharmaceutical ingredients (APIs).
• Used in asymmetric catalysis research as a potential ligand or catalyst precursor.
• Critical material in process chemistry for scaling up production of target molecules in medicinal chemistry.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Starting material for the synthesis of specialized compounds for biological activity screening.

Basic Information

Product Name	n-[(9S)-8Alpha-Cinchonan-9-Yl]Quinoline-8-Sulfonamide
CAS No.	1440939-88-7
Molecular Formula	C₂₇H₂₅N₃O₂S
Molecular Weight	455.57 g/mol
Synonyms	(8α,9S)-N-(Quinolin-8-yl)cinchonan-9-amine 8-sulfonamide; Cinchonan-9-amine, N-(8-quinolinyl)-, 8-sulfonamide, (8α,9S)-; Quinoline-8-sulfonamide, N-[(9S)-8α-cinchonan-9-yl]-; (9S)-N-(Quinolin-8-yl)cinchonan-9-amine 8-sulfonamide; 8-Quinolinesulfonamide, N-[(8α,9S)-cinchonan-9-yl]-; Chiral Cinchona Alkaloid Sulfonamide Derivative
EINECS	Contact for details

Quality Control

Our n-[(9S)-8Alpha-Cinchonan-9-Yl]Quinoline-8-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.