Description

1-Bromo-2,5-Difluoro-4-(Trifluoromethoxy)Benzene is a high-purity, multi-functional halogenated benzene derivative designed for advanced chemical synthesis. This compound matters as a critical building block for introducing bromine, fluorine, and trifluoromethoxy substituents into complex molecular architectures, enabling precise control over electronic and steric properties. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients, particularly in the creation of fluorinated drug candidates and specialty crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), especially in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy and difluoro groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with unique solubility, thermal, and surface properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new fluorination methodologies and creating novel chemical entities.

Basic Information

Product Name	1-Bromo-2,5-Difluoro-4-(Trifluoromethoxy)Benzene
CAS No.	1439904-14-9
Molecular Formula	C7H2BrF5O
Molecular Weight	276.99 g/mol
Synonyms	4-Bromo-1,4-difluoro-2-(trifluoromethoxy)benzene; 2,5-Difluoro-4-(trifluoromethoxy)bromobenzene; 1-Bromo-2,5-difluoro-4-(trifluoromethoxy)benzene; Benzene, 1-bromo-2,5-difluoro-4-(trifluoromethoxy)-; 4-Bromo-2,5-difluoro-1-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,5-Difluoro-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.