Description

(-)-1,13-Bis(Diphenyl)Phosphino-(5As,8As,14As)-5A,6,7,8,8A,9-Hexahydro-5H-[1]Benzopyrano [3,2-D]Xanthene CAS NO 1439556-82-7 is a sophisticated, chiral phosphine ligand with a unique, rigid backbone structure. This compound matters for its exceptional ability to induce high enantioselectivity in transition metal-catalyzed reactions, a critical factor in the synthesis of single-enantiomer pharmaceuticals and fine chemicals. It is primarily needed by research institutions and industrial R&D departments focused on asymmetric hydrogenation, cross-coupling, and other catalytic transformations.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the production of enantiomerically pure pharmaceutical intermediates.
• Catalyst component in cross-coupling reactions (e.g., Suzuki, Heck) requiring high stereochemical control.
• Key reagent in academic and industrial research for developing novel asymmetric synthetic methodologies.
• Use in the synthesis of complex natural products and agrochemicals where specific chirality is required for biological activity.
• Potential application in material science for creating chiral surfaces or polymers.

Basic Information

Product Name	(-)-1,13-Bis(Diphenyl)Phosphino-(5As,8As,14As)-5A,6,7,8,8A,9-Hexahydro-5H-[1]Benzopyrano [3,2-D]Xanthene
CAS No.	1439556-82-7
Molecular Formula	C45H36O2P2
Molecular Weight	670.71 g/mol
Synonyms	(-)-DTBM-SEGPHOS; (aS)-Bis(di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; (aS)-DTBM-SEGPHOS; (5As,8As,14As)-(-)-1,13-Bis(di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino)-5A,6,7,8,8A,9-hexahydro-5H-dibenzo[d,h][1,3,2]dioxaphosphepine; SEGPHOS derivative; Chiral diphosphine ligand; Asymmetric hydrogenation ligand.
EINECS	Contact for details

Quality Control

Our (-)-DTBM-SEGPHOS is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chiral purity, which is paramount for catalytic performance. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), it is recommended to store the product under an inert gas (argon or nitrogen) in a cool, dry place. For long-term stability, storage at 2-8°C is advised. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (ee)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.