Description

Zopiclone-D is a deuterated analog of the widely used sedative-hypnotic agent, Zopiclone. This compound is specifically designed for use as an internal standard in analytical chemistry, providing superior accuracy and reliability in quantitative analysis. It is an essential tool for researchers and quality control laboratories in the pharmaceutical and forensic science sectors who require precise measurement of Zopiclone and its metabolites.

Application

• Primary use as an Internal Standard for the quantitative analysis of Zopiclone via LC-MS/MS, GC-MS, and HPLC methods.
• Critical component in Bioanalytical Method Development and Validation for pharmacokinetic and pharmacodynamic studies.
• Used in Forensic Toxicology for the accurate identification and quantification of Zopiclone in biological samples.
• Essential for Pharmaceutical Quality Control labs to ensure batch consistency and purity of Zopiclone active pharmaceutical ingredients (APIs) and finished dosage forms.
• Supports Clinical Research involving sleep disorder treatments, enabling precise monitoring of drug levels.
• Facilitates Metabolite Studies due to its isotopic labeling, allowing for clear differentiation from the parent compound in complex matrices.

Basic Information

Product Name	Zopiclone-D
CAS No.	1435933-78-0
Molecular Formula	C17H14D3ClN6O3
Molecular Weight	391.81 g/mol
Synonyms	6-(5-Chloro-2-pyridinyl)-6,7-dihydro-7-(methyl-d3)-5H-pyrrolo[3,4-b]pyrazin-5-one; Deuterated Zopiclone; Zopiclone-d3; Zopiclone (methyl-d3); Zopiclone Internal Standard; Imovane-d3; Zimovane-d3; (RS)-6-(5-Chloropyridin-2-yl)-7-[(methyl-d3)oxy]-5,6-dihydropyrrolo[3,4-b]pyrazin-5-one
EINECS	Contact for details

Quality Control

Every batch of Zopiclone-D is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, Mass Spectrometry, and HPLC. A Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content is provided with each shipment to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 99.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.