Description

Albendazole-2-Aminosulfone-D3 Hydrochloride is a deuterated internal standard critical for ensuring the accuracy and reliability of quantitative mass spectrometry analysis. This high-purity reference material is essential for researchers and quality control laboratories requiring precise measurement of albendazole metabolites and related compounds. It is primarily utilized in the pharmaceutical and analytical chemistry sectors for method development, validation, and regulatory compliance testing.

Application

• Mass Spectrometry Internal Standard: Used as a deuterium-labeled internal standard for the accurate quantification of albendazole and its metabolites (e.g., albendazole sulfoxide, albendazole sulfone) in biological matrices via LC-MS/MS and GC-MS.
• Pharmaceutical R&D: Supports pharmacokinetic, bioavailability, and bioequivalence studies by providing a stable isotopic tracer for drug metabolism and disposition investigations.
• Veterinary Drug Residue Analysis: Enables precise monitoring and confirmation of albendazole residues in food-producing animals, meat, milk, and other products to ensure food safety and compliance with maximum residue limits (MRLs).
• Clinical Toxicology: Facilitates the accurate measurement of drug levels in human plasma or serum for therapeutic drug monitoring and overdose cases.
• Regulatory Compliance & Method Validation: A key component in developing and validating analytical methods according to guidelines from agencies like the FDA, EMA, and other global regulatory bodies.
• Reference Material for Quality Control: Serves as a certified reference material (CRM) for calibrating instruments and verifying the performance of analytical methods in QC laboratories.

Basic Information

Product Name	Albendazole-2-Aminosulfone-D3 Hydrochloride
CAS No.	1435902-07-0
Molecular Formula	C12H12D3N3O2S • HCl
Molecular Weight	313.82 g/mol (for free base C12H12D3N3O2S)
Synonyms	Albendazole Sulfone D3 Hydrochloride; Albendazole-2-aminosulfone-d3 HCl; 2-Aminosulfone Albendazole D3 Hydrochloride; 5-(Propylsulfonyl)-1H-benzimidazol-2-amine-d3 hydrochloride; Albendazole Sulfone-d3 (2-amino) Hydrochloride; [2H3]-Albendazole 2-Aminosulfone Hydrochloride; Internal Standard for Albendazole Sulfone
EINECS	Contact for details

Quality Control

Our Albendazole-2-Aminosulfone-D3 Hydrochloride is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical reference standards. Each batch undergoes comprehensive testing, including chromatographic purity assay, isotopic enrichment verification, and structural confirmation. A detailed Certificate of Analysis (COA) is provided, which includes batch-specific data on purity, water content, residual solvents, and NMR/LC-MS characterization to support your regulatory submissions and internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Keep container tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.