Description

Bcn-S-S-Amine CAS NO 1435784-65-8 is a specialized bifunctional chemical building block featuring a benzyloxycarbonyl (Bcn) protected amine group linked via a disulfide (S-S) bridge. This compound is valued for its unique dual functionality, enabling its use as a key intermediate in the synthesis of complex molecules where controlled release or reversible linkage is required. It is primarily sought after by researchers and process chemists in the pharmaceutical, biotechnology, and advanced materials sectors for applications in drug discovery, bioconjugation, and polymer chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for prodrug strategies.
• Bioconjugation & Probe Development: Utilized for creating cleavable linkers in antibody-drug conjugates (ADCs), imaging probes, and diagnostic reagents where a reducible disulfide bond is advantageous.
• Polymer & Materials Science: Acts as a functional monomer or cross-linking agent for developing stimuli-responsive polymers and smart materials.
• Peptide Synthesis: Employed in solid-phase peptide synthesis (SPPS) for the selective introduction of protected amine functionalities via disulfide chemistry.
• Chemical Biology Research: A valuable tool for studying protein interactions, enzyme mechanisms, and cellular uptake pathways that involve disulfide bond exchange.
• Controlled Release Systems: Incorporated into delivery systems where the disulfide bond provides a mechanism for triggered release in specific biological environments.

Basic Information

Product Name	Bcn-S-S-Amine
CAS No.	1435784-65-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-(((Benzyloxy)carbonyl)amino)-2-(2-((((benzyloxy)carbonyl)amino)ethyl)disulfanyl)ethane; Bcn-S-S-NH2; BCN protected disulfide amine; (2-((2-(((Benzyloxy)carbonyl)amino)ethyl)disulfanyl)ethyl)carbamic acid benzyl ester; Benzyl N-[2-[[2-(benzyloxycarbonylamino)ethyl]disulfanyl]ethyl]carbamate
EINECS	Contact for details

Quality Control

Our Bcn-S-S-Amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.