Description

tert-Butyl n-(2,2-Dimethyl-3-Oxocyclobutyl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclobutane ring structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise stereochemistry and functional group protection are required. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Organic Synthesis Reagent: Used in academic and industrial R&D laboratories for constructing cyclobutane-containing molecules, a valuable scaffold in medicinal chemistry.
• Peptidomimetics Research: Serves as a protected amino acid derivative analog for the development of peptide-like compounds with enhanced metabolic stability.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules in pilot plants and commercial manufacturing.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group provides a stable, acid-labile protecting group for amines during complex synthetic sequences.

Basic Information

Product Name	tert-Butyl n-(2,2-Dimethyl-3-Oxocyclobutyl)Carbamate
CAS No.	1434141-90-8
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	Boc-2,2-Dimethyl-3-oxocyclobutylamine; 1,1-Dimethyl-3-oxocyclobutylcarbamic acid tert-butyl ester; tert-Butyl (2,2-dimethyl-3-oxocyclobutyl)carbamate; N-Boc-2,2-dimethyl-3-oxocyclobutanamine; 2,2-Dimethyl-3-oxocyclobutylcarbamic acid tert-butyl ester; (2,2-Dimethyl-3-oxocyclobutyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(2,2-Dimethyl-3-Oxocyclobutyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.