Description

4-Fluoro-2-Cyclopropyliodobenzene is a high-value organoiodine building block characterized by its cyclopropyl and fluorine substituents on an aromatic ring. This compound is essential for advanced organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used to create novel herbicides and pesticides by introducing the cyclopropyl moiety into lead structures.
• Material Science: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed couplings (e.g., Suzuki, Stille, Negishi) to form biaryl and other conjugated systems.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and molecular recognition studies.
• Chemical Biology Probes: Used to tag or modify biomolecules for imaging and diagnostic applications.

Basic Information

Product Name	4-Fluoro-2-Cyclopropyliodobenzene
CAS No.	1434128-29-6
Molecular Formula	C9H8FI
Molecular Weight	262.06 g/mol
Synonyms	2-Cyclopropyl-4-fluoroiodobenzene; 1-Cyclopropyl-2-fluoro-4-iodobenzene; 4-Fluoro-2-cyclopropyl-1-iodobenzene; (4-Fluoro-2-cyclopropylphenyl)iodide; Benzene, 1-cyclopropyl-2-fluoro-4-iodo-; 4-Fluoro-2-cyclopropylphenyl iodide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Cyclopropyliodobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.