Description

(R)-Piperidine-2-Carbonitrile is a high-value chiral building block and key intermediate in organic synthesis. Its enantiopure structure is critical for imparting specific biological activity in advanced pharmaceutical compounds. This product is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients with high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurologically active drugs and enzyme inhibitors.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of novel chiral ligands for asymmetric hydrogenation and other catalytic transformations.
• Agrochemical Research: Serves as a building block for creating novel herbicides, fungicides, and insecticides with targeted modes of action.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, alkaloids, and other specialty chemicals.
• Chemical Biology & Proteomics: Utilized as a scaffold or labeling agent in the development of chemical probes and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers with specific chiral properties.

Basic Information

Item	Detail
Product Name	(R)-Piperidine-2-Carbonitrile
CAS No.	1434126-85-8
Molecular Formula	C6H10N2
Molecular Weight	110.16 g/mol
Synonyms	(R)-2-Cyanopiperidine; (R)-Piperidine-2-carbonitrile; (2R)-Piperidine-2-carbonitrile; (R)-2-Piperidinecarbonitrile; (R)-Azetidine-2-carbonitrile (related structure); (R)-Hexahydro-2-cyanopyridine; (R)-2-Cyano-piperidine; (R)-2-Piperidyl cyanide
EINECS	Contact for details

Quality Control

Our (R)-Piperidine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), enantiomeric excess (ee), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.