Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Homolysine(Boc)-Oh is a specialized, high-purity amino acid derivative designed for advanced peptide synthesis and pharmaceutical research. This compound is critical for introducing the D-homolysine residue with orthogonal protecting groups (Fmoc and Boc), enabling precise control over peptide chain assembly. It is an essential building block for researchers and manufacturers in the fields of medicinal chemistry, peptide drug development, and biochemical research, where structural complexity and chiral purity are paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the controlled incorporation of D-homolysine into custom peptide sequences.
• Medicinal Chemistry & Drug Discovery: Used in the research and development of novel peptide-based therapeutics, including antimicrobial peptides and hormone analogs.
• Bioconjugation: Serves as a functionalized linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or drug delivery systems.
• Chemical Biology Probes: Enables the synthesis of labeled or modified peptides for studying protein-protein interactions and cellular processes.
• Process Development: Employed in scaling up the production of peptide active pharmaceutical ingredients (APIs) under current Good Manufacturing Practice (cGMP) guidelines.
• Academic & Institutional Research: A fundamental reagent for exploring peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Homolysine(Boc)-Oh
CAS No.	1434054-86-0
Molecular Formula	C26H32N2O6
Molecular Weight	468.55 g/mol
Synonyms	Fmoc-D-Homolys(Boc)-OH; Nα-Fmoc-Nε-Boc-D-homolysine; Nα-(9-Fluorenylmethoxycarbonyl)-Nε-(tert-butoxycarbonyl)-D-homolysine; Fmoc-D-Hly(Boc)-OH; D-Homolysine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-[(1,1-dimethylethoxy)carbonyl]-; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-(tert-butoxycarbonyl)-D-homolysine; Fmoc-D-Lys(Boc)-OH homologue; Boc-D-Homolys(Fmoc)-OH
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Homolysine(Boc)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity, suitable for demanding research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to industry best practices and can provide material traceable to relevant standards for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.