Description

4-Chloro-1H-Indazole-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its indazole core structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in the development of targeted therapies, particularly within oncology and other therapeutic areas requiring heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted small molecules.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects under GMP or non-GMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental research on heterocyclic chemistry and bioactivity.

Basic Information

Product Name	4-Chloro-1H-Indazole-3-Carboxamide
CAS No.	1432754-19-2
Molecular Formula	C8H6ClN3O
Molecular Weight	195.61 g/mol
Synonyms	4-Chloro-1H-indazole-3-carboxamide; 4-Chloroindazole-3-carboxamide; 1H-Indazole-3-carboxamide, 4-chloro-; 4-Chloro-1H-indazole-3-carboxylic acid amide; 4-Chloroindazole-3-carboxylic acid amide; 1432754-19-2; 4-Cl-1H-indazole-3-CONH2
EINECS	Contact for details

Quality Control

Our 4-Chloro-1H-Indazole-3-Carboxamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation. Certificates of Analysis (COA) are available for every batch and supplied upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.