Description

Ethyl 2-Amino-2-(3-Bromo-4-Methoxyphenyl)Acetate Hydrochloride is a high-purity, non-natural amino acid derivative and a key chiral building block in advanced organic synthesis. This compound is critical for research and development in pharmaceutical chemistry, enabling the construction of complex molecules with precise stereochemistry. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides.
• Peptidomimetics Research: Serves as a constrained amino acid analog for designing and synthesizing novel peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme mechanisms and biological pathways.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for synthesizing chiral ligands and catalysts used in stereoselective transformations.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting cutting-edge synthetic methodology and medicinal chemistry projects.

Basic Information

Product Name	Ethyl 2-Amino-2-(3-Bromo-4-Methoxyphenyl)Acetate Hydrochloride
CAS No.	1432677-66-1
Molecular Formula	C11H15BrClNO3
Molecular Weight	324.60 g/mol
Synonyms	Ethyl 2-Amino-2-(3-Bromo-4-Methoxyphenyl)Acetate HCl; 2-Amino-2-(3-bromo-4-methoxyphenyl)acetic acid ethyl ester hydrochloride; Ethyl α-Amino-(3-bromo-4-methoxyphenyl)acetate Hydrochloride; (3-Bromo-4-methoxyphenyl)glycine ethyl ester hydrochloride; (R/S)-Ethyl 2-amino-2-(3-bromo-4-methoxyphenyl)acetate hydrochloride; Amino(3-bromo-4-methoxyphenyl)acetic acid ethyl ester hydrochloride; AGN-PC-0E7QKX (possible research code)
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-2-(3-Bromo-4-Methoxyphenyl)Acetate Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing HPLC purity, chiral purity, NMR, and mass spectrometry data is supplied with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.