Description

4,5-Difluoro-2-Formylphenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl group and a boronic acid moiety on a difluorinated aromatic ring, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for applications in Suzuki-Miyaura cross-coupling reactions and other catalytic transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the difluoro and formyl groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics (OPVs).
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4,5-Difluoro-2-Formylphenylboronic Acid
CAS No.	1432610-24-6
Molecular Formula	C7H5BF2O3
Molecular Weight	185.92 g/mol
Synonyms	(4,5-Difluoro-2-formylphenyl)boronic acid; 2-Borono-4,5-difluorobenzaldehyde; 4,5-Difluorobenzaldehyde-2-boronic acid; 4,5-Difluoro-2-carboxyphenylboronic Acid (tautomer); 2-Formyl-4,5-difluorophenylboronic Acid; 4,5-DF2FPBA; 1432610-24-6 (CAS)
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements of research and industrial applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.