Description

(S)-2-Ethylpyrrolidine-2-Carboxylic Acid Hydrochloride is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a key precursor for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure components for advanced R&D and production.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Asymmetric Synthesis: Serves as a versatile building block in asymmetric synthesis for constructing complex, enantiomerically pure molecular architectures.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for stereoselective transformations.
• Agrochemical Research: Employed as an intermediate in the synthesis of advanced, enantiopure agrochemicals and plant protection agents.
• Peptidomimetics and Bioactive Molecules: Functions as a constrained proline analog for designing peptidomimetics and other bioactive compounds with improved metabolic stability.
• Academic and Industrial R&D: A valuable reagent for chemical research in academic institutions and corporate R&D laboratories focused on medicinal chemistry and process development.

Basic Information

Product Name	(S)-2-Ethylpyrrolidine-2-Carboxylic Acid Hydrochloride
CAS No.	1431699-61-4
Molecular Formula	C7H13NO2 • HCl
Molecular Weight	179.64 g/mol (Free base: 143.18 g/mol)
Synonyms	(S)-2-Ethyl-2-pyrrolidinecarboxylic acid hydrochloride; (2S)-2-Ethylpyrrolidine-2-carboxylic acid hydrochloride; L-2-Ethylproline hydrochloride; (S)-2-Ethylproline HCl; (S)-2-Carboxy-2-ethylpyrrolidine hydrochloride; 2-Ethyl-DL-proline hydrochloride (for racemic mixture reference); Proline, 2-ethyl-, hydrochloride, (S)-
EINECS	Contact for details

Quality Control

Our (S)-2-Ethylpyrrolidine-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.