Description

Potassium 2-Iodophenyltrifluoroborate is a versatile and highly valuable organoboron reagent, specifically an aryltrifluoroborate salt. Its primary value lies in its exceptional stability and reactivity, making it a superior alternative to traditional boronic acids in cross-coupling reactions, particularly under challenging conditions. This compound is essential for researchers and manufacturers in pharmaceutical development and advanced material science who require reliable, high-purity building blocks for complex organic synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this iodophenyl moiety, crucial for constructing complex biaryl structures found in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and production of drug candidates, especially those containing iodine-substituted aromatic rings for further functionalization or as a pharmacophore.
• Agrochemical and Fine Chemical Manufacturing: Serves as a building block for creating novel compounds with specific biological activities for crop protection and specialty chemicals.
• Material Science and OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and emissive materials for electronic devices due to its stable boronate structure.
• Chemical Biology and Probe Development: Useful for bioconjugation and labeling strategies where a stable, yet reactive, aryl handle is required.
• Scale-up Process Chemistry: Its air and moisture stability compared to boronic acids makes it advantageous for robust, reproducible manufacturing processes.

Basic Information

Product Name	Potassium 2-Iodophenyltrifluoroborate
CAS No.	1431616-58-8
Molecular Formula	C6H4BF3IK
Molecular Weight	303.91 g/mol
Synonyms	Potassium (2-Iodophenyl)trifluoroborate; 2-Iodophenyltrifluoroborate Potassium Salt; Potassium 2-Iodobenzene-1-trifluoroborate; (2-Iodophenyl)trifluoroboronic Acid Potassium Salt; 2-Iodo-Benzenetrifluoroborate Potassium Salt; Potassium Trifluoro(2-iodophenyl)borate; 2-Iodophenyl Potassium Trifluoroborate; Potassium Trifluoro(2-iodobenzene)borate(1-)
EINECS	Contact for details

Quality Control

Our Potassium 2-Iodophenyltrifluoroborate is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity. Optimal storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (NMR / HPLC)	≥95%
Water Content (KF)	≤2.0%
NMR Purity (19F / 11B)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.