Description

4-Chloro-3-Fluoro-5-(Trifluoromethyl)Phenylaceticacid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring multiple halogen substituents, makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and specific physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl and halogen groups contribute to efficacy.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Specialty Polymer Modifier: Incorporated to introduce specific functional groups into polymer chains, altering material properties like chemical resistance or thermal stability.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination chemistry and structure-activity relationships.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	4-Chloro-3-Fluoro-5-(Trifluoromethyl)Phenylaceticacid
CAS No.	1431329-73-5
Molecular Formula	C9H5ClF4O2
Molecular Weight	256.58 g/mol
Synonyms	[2-(4-Chloro-3-fluoro-5-(trifluoromethyl)phenyl]acetic acid; 4-Chloro-3-fluoro-α-(trifluoromethyl)benzeneacetic acid; 2-(4-Chloro-3-fluoro-5-(trifluoromethyl)phenyl)ethanoic acid; 1431329-73-5; 4-Chloro-3-fluoro-5-trifluoromethylphenylacetic acid; Acetic acid, 2-[4-chloro-3-fluoro-5-(trifluoromethyl)phenyl]-; (4-Chloro-3-fluoro-5-(trifluoromethyl)phenyl)acetic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluoro-5-(Trifluoromethyl)Phenylaceticacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.