Description

3-Chloro-2-Fluoro-4-(Trifluoromethyl)Phenylaceticacid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated trifluoromethylphenylacetic acid structure imparts desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new products.

Application

• As a critical pharmaceutical intermediate in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting inflammation, oncology, and central nervous system disorders.
• Utilized as a key building block for the development of advanced agrochemicals, including next-generation herbicides, fungicides, and plant growth regulators.
• Serves as a versatile precursor in organic synthesis for introducing the chlorinated, fluorinated, and trifluoromethylated phenylacetic acid moiety into complex molecules.
• Used in material science research for the creation of specialty polymers and liquid crystals with tailored properties.
• Acts as a starting material or intermediate in custom synthesis and contract manufacturing for clients requiring specific fluorinated aromatic compounds.

Basic Information

Product Name	3-Chloro-2-Fluoro-4-(Trifluoromethyl)Phenylaceticacid
CAS No.	1431329-72-4
Molecular Formula	C9H5ClF4O2
Molecular Weight	256.58 g/mol
Synonyms	2-(3-Chloro-2-fluoro-4-(trifluoromethyl)phenyl)acetic acid; 3-Chloro-2-fluoro-4-(trifluoromethyl)benzeneacetic acid; α-(3-Chloro-2-fluoro-4-(trifluoromethyl)phenyl)acetic acid; (3-Chloro-2-fluoro-4-(trifluoromethyl)phenyl)acetic acid; 3-Chloro-2-fluoro-α-(trifluoromethyl)benzeneacetic acid; 1431329-72-4; 3-Chloro-2-fluoro-4-trifluoromethylphenylacetic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-4-(Trifluoromethyl)Phenylaceticacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, providing full traceability and compliance assurance for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.