Description

4-Chloro-3-Fluoro-5-(Trifluoromethyl)Phenylacetonitrile is a high-value, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. This compound is critical for research and development in the agrochemical and pharmaceutical sectors, where its unique halogenated and trifluoromethylated structure enables the creation of novel active ingredients. It is primarily sought by fine chemical manufacturers and R&D laboratories engaged in developing next-generation crop protection agents and pharmaceutical intermediates.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and halogen substituents.
• Pharmaceutical Building Block: Used in medicinal chemistry for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands and catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and polymers with specific electronic or optical properties.
• Custom Synthesis and Contract Manufacturing: An essential substrate for custom synthesis services catering to the specific needs of agrochemical and pharmaceutical companies.

Basic Information

Product Name	4-Chloro-3-Fluoro-5-(Trifluoromethyl)Phenylacetonitrile
CAS No.	1431329-62-2
Molecular Formula	C9H4ClF4N
Molecular Weight	237.58 g/mol
Synonyms	2-(4-Chloro-3-fluoro-5-(trifluoromethyl)phenyl)acetonitrile; (4-Chloro-3-fluoro-5-(trifluoromethyl)phenyl)acetonitrile; 4-Chloro-3-fluoro-α,α,α-trifluoro-m-toluonitrile; 2-(4-Chloro-3-fluoro-5-(trifluoromethyl)phenyl)ethanenitrile; 4-Chloro-3-fluoro-5-trifluoromethylbenzyl cyanide
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluoro-5-(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with the stringent requirements of GMP for pharmaceutical intermediates and ISO standards for industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.