Description

Propargyl-Peg5-Ch2Co2H is a high-purity, heterobifunctional polyethylene glycol (PEG) linker featuring a propargyl group and a carboxylic acid terminus. This compound is essential for advanced bioconjugation and click chemistry applications, enabling the precise and efficient coupling of biomolecules, polymers, and surfaces. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and materials science sectors for developing drug delivery systems, diagnostic reagents, and functionalized nanomaterials.

Application

• Bioconjugation Reagent: Used for site-specific labeling of peptides, proteins, and antibodies via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Drug Delivery System Development: Serves as a key building block for creating PEGylated drug conjugates, enhancing solubility, stability, and pharmacokinetic profiles of active pharmaceutical ingredients (APIs).
• Polymer and Dendrimer Synthesis: Acts as a functional monomer or crosslinker for synthesizing advanced polymeric architectures with tailored properties.
• Surface Functionalization: Enables the modification of nanoparticles, biosensors, and chromatographic media with bioactive ligands for targeted applications.
• Diagnostic Assay Development: Facilitates the creation of stable, high-sensitivity probes and labels for immunoassays and molecular imaging.
• Hydrogel Formation: Used in the preparation of crosslinked hydrogel networks for tissue engineering and controlled release matrices.

Basic Information

Product Name	Propargyl-Peg5-Ch2Co2H
CAS No.	1429934-37-1
Molecular Formula	C20H34O9
Molecular Weight	418.48 g/mol
Synonyms	Propargyl-PEG5-acid; Propargyl-PEG5-CH2COOH; 2,5,8,11,14-Pentaoxaheptadec-16-ynoic acid; Propargyl-O-(CH2CH2O)5-CH2COOH; 5K Propargyl-PEG4-acetic acid; Propargyl-Pentaethylene glycol-acetic acid; Alkyne-PEG5-acid; Propargyl PEG Acid (MW 418)
EINECS	Contact for details

Quality Control

Our Propargyl-Peg5-Ch2Co2H is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) in a dry, cool environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.